LSD Is Becoming Medicine Again

Channel: Mushies

LSD has had one of the strangest journeys of any drug in modern history. First synthesised in 1938, it went from an experimental pharmaceutical compound to a psychiatric research tool, a possible treatment for alcoholism, an icon of the 1960s counterculture, and eventually one of the world’s most notorious illegal drugs. Now scientists are studying it again. In this video, I look at the history of LSD, what it actually does in the brain, why researchers think it may temporarily alter the way brain networks communicate, and the emerging evidence around anxiety, depression, learning and neuroplasticity. Recent brain-imaging and computational studies suggest LSD can alter local brain synchronisation and shift the brain toward more globally synchronised, less modular states. And in 2026, a ran

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